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Disorders of Mood
How does the brain function differently when a person is suffering from a major, clinical depression? Can differences in brain structure and function be related to the development of a mood disorder? Can measures of brain function be used to predict which antidepressant medication will be successful for treatment of a particular patient? Can changes in brain function during treatment be used clinically to guide treatment? How do different types of medication affect the brain? We have undertaken open-label studies in which patients receive "care as usual," as well as controlled clinical trials using double-masked placebo controlled designs and specific antidepressant medications. A number of our projects are currently enrolling subjects who live in the Los Angeles area, and more information can be obtained by calling our study hotline at (310) 825-3351.
support from NARSAD (Dr. Cook, PI), NIH grants R01 MH40705 (Dr. Leuchter, PI), and industrial support from a number of different manufacturers of antidepressant medications
